acanthoma|acanthomas|acanthomata in English

noun

[ə'kænθ'əʊmʌ]

tumor in the epidermis

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1. Both the clinical features and pathology were typical for disseminated epidermolytic acanthomas.

2. Clear cell acanthoma is a rare, slow-growing benign epidermal tumour of adulthood.

3. In 2005, "Acanthoma" was added to MeSH as an index term; previous indexing was "Skin Neoplasms" (1965–2004).

4. Multiple clear cell acanthomas are very rare and are also found in other locations besides the typical site of predilection.

5. Epidermolytic acanthomas are acquired, harmless lesions and must be differentiated from more serious, congenital ichthyoses of the skin, showing the same histopathologic picture.

6. In the case of viral acanthomas, the stratum spinosum and granulosum presents ballooned cells which contain all transitional stages from multivesicular bodies (MVB) to kerationsomes.

7. In the course of this disease two carcinomas of the colon, a kerato-acanthoma and multiple sebaceous gland tumours, including four sebaceous gland tumours, including four sebaceous carcinomas, appeared.

8. The participation of intercellular extruded “wagon-wheel” bodies, MVB and atypical keratinosomes on an irregular baso-apical diffusion-barrier in the epidermis of cases with viral acanthomas has been discussed.

9. As a class effect, BRAF-inhibitors induce proliferative disorders of keratinocytes and melanocytes, such as palmoplantar hyperkeratosis (as part of the hand-foot syndrome), verruciform and acanthoma-like lesions, follicular and Grover disease-like hyperkeratoses, keratoacanthomas, squamous cell carcinomas and atypical melanocytic nevi with transition to secondary melanomas.

10. Based on histology and electron microscopy, a series of Papova virus acanthomas consisting of 300 common warts and Condylomata acuminata as well as primary efflorescences of 7 typical and 7 questionable cases of Epidermodysplasia verruciformis have been classified. Four cytological types expressing different cytopathogenic viral actions were established.

11. On the basis of the relation seen between MVB and the Golgi-apparatus, their transition to partially atypical keratinosomes in cases of viral acanthomas and their “expulsion” into the intercellular space could indicate that in keratinozytes the enzymatically regulated feed-back between the cellular surface and the capability to synthesize is changed by viral agents.